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Structure paper

TitleDirect binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Journal, issue, pagesLife Sci Alliance, Vol. 1, Page e201800238-e201800238, Year 2018
Publish dateDec 25, 2018 (structure data deposition date)
AuthorsHayashi, A. / Giakoumakis, N.N. / Heidebrecht, T. / Ishii, T. / Panagopoulos, A. / Caillat, C. / Takahara, M. / Hibbert, R.G. / Suenaga, N. / Stadnik-Spiewak, M. ...Hayashi, A. / Giakoumakis, N.N. / Heidebrecht, T. / Ishii, T. / Panagopoulos, A. / Caillat, C. / Takahara, M. / Hibbert, R.G. / Suenaga, N. / Stadnik-Spiewak, M. / Takahashi, T. / Shiomi, Y. / Taraviras, S. / von Castelmur, E. / Lygerou, Z. / Perrakis, A. / Nishitani, H.
External linksLife Sci Alliance / PubMed:30623174
MethodsX-ray diffraction
Resolution3.4 - 3.5 Å
Structure data

PDB-6qc0:
PCNA complex with Cdt2 C-terminal PIP-box peptide
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-6qcg:
PCNA complex with Cdt1 N-terminal PIP-box peptide
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsREPLICATION / complex / PIP / CELL CYCLE / dna replication / ubiquitination / clr4

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