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TitleThe Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Journal, issue, pagesMol. Cell, Vol. 73, Page 490-504.e6, Year 2019
Publish dateApr 10, 2018 (structure data deposition date)
AuthorsLoughlin, F.E. / Lukavsky, P.J. / Kazeeva, T. / Reber, S. / Hock, E.M. / Colombo, M. / Von Schroetter, C. / Pauli, P. / Clery, A. / Muhlemann, O. ...Loughlin, F.E. / Lukavsky, P.J. / Kazeeva, T. / Reber, S. / Hock, E.M. / Colombo, M. / Von Schroetter, C. / Pauli, P. / Clery, A. / Muhlemann, O. / Polymenidou, M. / Ruepp, M.D. / Allain, F.H.
External linksMol. Cell / PubMed:30581145
MethodsNMR (solution)
Structure data

PDB-6g99:
Solution structure of FUS-ZnF bound to UGGUG
Method: SOLUTION NMR

PDB-6gbm:
Solution structure of FUS-RRM bound to stem-loop RNA
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / RNA zinc finger RNA binding protein zinc ribbon / RNA / RNA recognition motif / RRM

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