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Structure paper

TitleStructural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.
Journal, issue, pagesNat. Chem. Biol., Vol. 15, Page 132-140, Year 2019
Publish dateMay 4, 2018 (structure data deposition date)
AuthorsYang, Y. / Eichhorn, C.D. / Wang, Y. / Cascio, D. / Feigon, J.
External linksNat. Chem. Biol. / PubMed:30559425
MethodsX-ray diffraction
Resolution1.998 - 2.1 Å
Structure data

PDB-6dcb:
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Method: X-RAY DIFFRACTION / Resolution: 1.998 Å

PDB-6dcc:
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/RNA / RNA methyl transferase / MePCE / 7SK RNA / Transferase-RNA complex

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