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Structure paper

TitleMechanistic insights revealed by a UBE2A mutation linked to intellectual disability.
Journal, issue, pagesNat. Chem. Biol., Vol. 15, Page 62-70, Year 2019
Publish dateApr 6, 2018 (structure data deposition date)
Authorsde Oliveira, J.F. / do Prado, P.F.V. / da Costa, S.S. / Sforca, M.L. / Canateli, C. / Ranzani, A.T. / Maschietto, M. / de Oliveira, P.S.L. / Otto, P.A. / Klevit, R.E. ...de Oliveira, J.F. / do Prado, P.F.V. / da Costa, S.S. / Sforca, M.L. / Canateli, C. / Ranzani, A.T. / Maschietto, M. / de Oliveira, P.S.L. / Otto, P.A. / Klevit, R.E. / Krepischi, A.C.V. / Rosenberg, C. / Franchini, K.G.
External linksNat. Chem. Biol. / PubMed:30531907
MethodsX-ray diffraction
Resolution1.85 - 2.2 Å
Structure data

PDB-6cyo:
Crystal structure of human UBE2A (RAD6A)
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-6cyr:
Crystal structure of the UBE2A variant Q93E
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / TRANSFERASE / Ubiquitin-Conjungating enzyme E2 A / Q93E variant

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