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TitleStructural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
Journal, issue, pagesJ. Mol. Biol., Vol. 431, Page 714-731, Year 2019
Publish dateJul 20, 2018 (structure data deposition date)
AuthorsScheide-Noeth, J.P. / Rosen, M. / Baumstark, D. / Dietz, H. / Mueller, T.D.
External linksJ. Mol. Biol. / PubMed:30529748
MethodsX-ray diffraction
Resolution2.75 Å
Structure data

PDB-6h41:
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsCYTOKINE / Interleukin-5 / inhibitor peptide / peptide-receptor complex / atopic diseases

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