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Structure paper

TitleCrystal structures of human ETBreceptor provide mechanistic insight into receptor activation and partial activation.
Journal, issue, pagesNat Commun, Vol. 9, Page 4711-4711, Year 2018
Publish dateSep 25, 2018 (structure data deposition date)
AuthorsShihoya, W. / Izume, T. / Inoue, A. / Yamashita, K. / Kadji, F.M.N. / Hirata, K. / Aoki, J. / Nishizawa, T. / Nureki, O.
External linksNat Commun / PubMed:30413709
MethodsX-ray diffraction
Resolution2 - 2.7 Å
Structure data

PDB-6igk:
Crystal Structure of human ETB receptor in complex with Endothelin-3
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6igl:
Crystal Structure of human ETB receptor in complex with IRL1620
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • enterobacteria phage rb59 (virus)
KeywordsSIGNALING PROTEIN/PROTEIN BINDING / alpha helical / SIGNALING PROTEIN-PROTEIN BINDING complex / SIGNALING PROTEIN

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