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TitleLimited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Journal, issue, pagesCell Rep, Vol. 25, Page 909-920.e4, Year 2018
Publish dateJun 17, 2018 (structure data deposition date)
AuthorsLi, Y. / Tan, S. / Zhang, C. / Chai, Y. / He, M. / Zhang, C.W. / Wang, Q. / Tong, Z. / Liu, K. / Lei, Y. ...Li, Y. / Tan, S. / Zhang, C. / Chai, Y. / He, M. / Zhang, C.W. / Wang, Q. / Tong, Z. / Liu, K. / Lei, Y. / Liu, W.J. / Liu, Y. / Tian, Z. / Cao, X. / Yan, J. / Qi, J. / Tien, P. / Gao, S. / Gao, G.F.
External linksCell Rep / PubMed:30355497
MethodsX-ray diffraction
Resolution2 - 3.391 Å
Structure data

PDB-6a3v:
Complex structure of human 4-1BB and 4-1BBL
Method: X-RAY DIFFRACTION / Resolution: 3.391 Å

PDB-6a3w:
Complex structure of 4-1BB and utomilumab
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / complex structure / agonist monoclonal antibody / cross-linking / 4-1BB / angonist monoclonal antibody

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