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TitleMapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries.
Journal, issue, pagesNat Commun, Vol. 9, Page 3935-3935, Year 2018
Publish dateApr 30, 2018 (structure data deposition date)
AuthorsNaftaly, S. / Cohen, I. / Shahar, A. / Hockla, A. / Radisky, E.S. / Papo, N.
External linksNat Commun / PubMed:30258049
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-6gfi:
Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / protein protein interactions / serine proteases / amyloid protein precursor inhibitor

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