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-Structure paper
Title | Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer. |
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Journal, issue, pages | Mol. Cancer Ther., Vol. 17, Page 2519-2529, Year 2018 |
Publish date | Nov 30, 2016 (structure data deposition date) |
![]() | Tanaka, H. / Sase, H. / Tsukaguchi, T. / Hasegawa, M. / Tanimura, H. / Yoshida, M. / Sakata, K. / Fujii, T. / Tachibana, Y. / Takanashi, K. ...Tanaka, H. / Sase, H. / Tsukaguchi, T. / Hasegawa, M. / Tanimura, H. / Yoshida, M. / Sakata, K. / Fujii, T. / Tachibana, Y. / Takanashi, K. / Higashida, A. / Hasegawa, K. / Ono, Y. / Oikawa, N. / Mio, T. |
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Methods | X-ray diffraction |
Resolution | 2.76 Å |
Structure data | ![]() PDB-5wr7: |
Chemicals | ![]() ChemComp-RCH: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / TRK-A / KINASE DOMAIN / HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR / PROTEROS BIOSTRUCTURES GMBH / TRANSFERASE-TRANSFERASE INHIBITOR complex |