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Structure paper

TitleEFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies.
Journal, issue, pagesMAbs, Vol. 10, Page 1248-1259, Year 2018
Publish dateMar 16, 2018 (structure data deposition date)
AuthorsCooke, H.A. / Arndt, J. / Quan, C. / Shapiro, R.I. / Wen, D. / Foley, S. / Vecchi, M.M. / Preyer, M.
External linksMAbs / PubMed:30215570
MethodsX-ray diffraction
Resolution1.521 Å
Structure data

PDB-6cr1:
adalimumab EFab
Method: X-RAY DIFFRACTION / Resolution: 1.521 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / EFab / IgE

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