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TitleStructural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
Journal, issue, pagesChemistryOpen, Vol. 7, Page 721-727, Year 2018
Publish dateAug 18, 2017 (structure data deposition date)
AuthorsOhbayashi, N. / Murayama, K. / Kato-Murayama, M. / Kukimoto-Niino, M. / Uejima, T. / Matsuda, T. / Ohsawa, N. / Yokoyoma, S. / Nojima, H. / Shirouzu, M.
External linksChemistryOpen / PubMed:30214852
MethodsX-ray diffraction
Resolution2.5 - 2.804 Å
Structure data

PDB-5y7z:
Complex structure of cyclin G-associated kinase with gefitinib
Method: X-RAY DIFFRACTION / Resolution: 2.804 Å

PDB-5y80:
Complex structure of cyclin G-associated kinase with gefitinib
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-IRE:
Gefitinib / medication, inhibitor*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsTRANSFERASE/IMMUNE SYSTEM / Kinase / complex / TRANSFERASE-IMMUNE SYSTEM complex

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