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TitleTrypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs.
Journal, issue, pagesStructure, Vol. 26, Page 1499-1512.e5, Year 2018
Publish dateMay 15, 2018 (structure data deposition date)
AuthorsAfanador, G.A. / Tomchick, D.R. / Phillips, M.A.
External linksStructure / PubMed:30197036
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-6dft:
Trypanosoma brucei deoxyhypusine synthase
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Source
  • trypanosoma brucei (eukaryote)
KeywordsTRANSFERASE / heterotetramer / Rossman fold / pseudoenzyme / NAD+

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