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TitleRecognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
Journal, issue, pagesFEBS Lett., Vol. 592, Page 3335-3345, Year 2018
Publish dateApr 17, 2018 (structure data deposition date)
AuthorsZagorskaite, E. / Manakova, E. / Sasnauskas, G.
External linksFEBS Lett. / PubMed:30194838
MethodsX-ray diffraction
Resolution1.55 - 1.8 Å
Structure data

PDB-6gcd:
DNA binding domain of restriction endonuclease McrBC in complex with 5-hydroxymethylcytosine DNA
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6gce:
DNA binding domain of restriction endonuclease McrBC in complex with 5-formylcytosine DNA
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6gcf:
DNA binding domain of restriction endonuclease McrBC in complex with N4-methylcytosine DNA
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / 5-hydroxymethylcytosine / restriction endonuclease / McrBC / base flipping / 5-formylcytosine / N4-methylcytosine

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