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TitleComplementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 16503-16517, Year 2018
Publish dateJun 26, 2018 (structure data deposition date)
AuthorsZuo, Y. / Wang, P. / Sun, J. / Guo, S. / Wang, G. / Zuo, T. / Fan, S. / Zhou, P. / Liang, M. / Shi, X. ...Zuo, Y. / Wang, P. / Sun, J. / Guo, S. / Wang, G. / Zuo, T. / Fan, S. / Zhou, P. / Liang, M. / Shi, X. / Wang, X. / Zhang, L.
External linksJ. Biol. Chem. / PubMed:30154240
MethodsX-ray diffraction
Resolution2.33 Å
Structure data

PDB-6a67:
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140
Method: X-RAY DIFFRACTION / Resolution: 2.33 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • influenza a virus (a/thailand/1(kan-1)/2004(h5n1))
KeywordsIMMUNE SYSTEM / influenza virus / H5N1 / neutralizing antibodies / receptor binding site

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