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Structure paper

TitleEnsemble Properties of Bax Determine Its Function.
Journal, issue, pagesStructure, Vol. 26, Page 1346-, Year 2018
Publish dateJun 16, 2017 (structure data deposition date)
AuthorsRobin, A.Y. / Iyer, S. / Birkinshaw, R.W. / Sandow, J. / Wardak, A. / Luo, C.S. / Shi, M. / Webb, A.I. / Czabotar, P.E. / Kluck, R.M. / Colman, P.M.
External linksStructure / PubMed:30122452
MethodsX-ray diffraction
Resolution1.803 - 2.502 Å
Structure data

PDB-5w5x:
Crystal structure of BAXP168G in complex with an activating antibody
Method: X-RAY DIFFRACTION / Resolution: 2.502 Å

PDB-5w5z:
Crystal structure of BAXP168G in complex with an activating antibody at high resolution
Method: X-RAY DIFFRACTION / Resolution: 1.997 Å

PDB-5w60:
Crystal structure of BAXP168G monomer cryo-protected with ethylene glycol
Method: X-RAY DIFFRACTION / Resolution: 1.803 Å

PDB-5w61:
Crystal structure of BAXP168G monomer co-crystallized with glycerol
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5w62:
Crystal structure of mouse BAX monomer
Method: X-RAY DIFFRACTION / Resolution: 2.196 Å

PDB-5w63:
Crystal structure of channel catfish BAX
Method: X-RAY DIFFRACTION / Resolution: 2.436 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
  • mus musculus (house mouse)
  • ictalurus punctatus (channel catfish)
KeywordsAPOPTOSIS/IMMUNE SYSTEM / Fab' / BAX activation / unfolding / APOPTOSIS / APOPTOSIS-IMMUNE SYSTEM complex / Fab / BAX / inactive monomer / monomer / mouse / catfish

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