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Structure paper

TitleStructures of Hepatitis B Virus Core- and e-Antigen Immune Complexes Suggest Multi-point Inhibition.
Journal, issue, pagesStructure, Vol. 26, Page 1314-, Year 2018
Publish dateMar 28, 2018 (structure data deposition date)
AuthorsEren, E. / Watts, N.R. / Dearborn, A.D. / Palmer, I.W. / Kaufman, J.D. / Steven, A.C. / Wingfield, P.T.
External linksStructure / PubMed:30100358
MethodsX-ray diffraction
Resolution2.38 - 3.33 Å
Structure data

PDB-6cvk:
Hepatitis B e-antigen in complex with scFv e13
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-6cwd:
Hepatitis B core-antigen in complex with scFv e13
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

PDB-6cwt:
Hepatitis B core-antigen in complex with Fab e21
Method: X-RAY DIFFRACTION / Resolution: 3.151 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
  • hepatitis b virus
  • hepatitis b virus subtype adyw
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / HEPATITIS B / SINGLE CHAIN VARIABLE FRAGMENT / E-ANTIGEN / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / core-antigen / nucleocapsid / scFv / Hepatitis B virus / Fab / Core dimer

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