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Structure paper

TitleTGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling.
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 9220-9235, Year 2018
Publish dateFeb 14, 2018 (structure data deposition date)
AuthorsGuca, E. / Sunol, D. / Ruiz, L. / Konkol, A. / Cordero, J. / Torner, C. / Aragon, E. / Martin-Malpartida, P. / Riera, A. / Macias, M.J.
External linksNucleic Acids Res. / PubMed:30060237
MethodsX-ray diffraction
Resolution2.42 - 3.25000253887 Å
Structure data

PDB-6fqp:
Crystal structure of TALE homeobox domain transcription factor TGIF1 with its consensus DNA
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-6fqq:
Crystal structure of TALE homeobox domain transcription factor TGIF1 double alanine mutant bound to its consensus DNA
Method: X-RAY DIFFRACTION / Resolution: 3.25000253887 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / homeobox / three-amino acid loop extension / TGF-beta pathway

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