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Structure paper

TitleStructural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 6893-6908, Year 2018
Publish dateDec 20, 2017 (structure data deposition date)
AuthorsGruner, S. / Weber, R. / Peter, D. / Chung, M.Y. / Igreja, C. / Valkov, E. / Izaurralde, E.
External linksNucleic Acids Res. / PubMed:30053226
MethodsX-ray diffraction
Resolution1.293 - 1.92 Å
Structure data

PDB-6fbz:
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
Method: X-RAY DIFFRACTION / Resolution: 1.496 Å

PDB-6fc0:
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum
Method: X-RAY DIFFRACTION / Resolution: 1.293 Å

PDB-6fc1:
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-6fc2:
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-6fc3:
Crystal structure of the eIF4E-p20 complex from Saccharomyces cerevisiae
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • chaetomium thermophilum var. thermophilum dsm 1495 (fungus)
  • saccharomyces cerevisiae s288c (yeast)
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsTRANSLATION / Translation Translational control Translation initiation Gene expression / Gene expression Translation Translation initiation Translational control / Gene expression Translation Translational control 4E-binding proteins / Translation Translational control Gene expression 4E-binding protein

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