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Structure paper

TitleCrystal structures of human procathepsin H.
Journal, issue, pagesPLoS ONE, Vol. 13, Page e0200374-e0200374, Year 2018
Publish dateApr 9, 2018 (structure data deposition date)
AuthorsHao, Y. / Purtha, W. / Cortesio, C. / Rui, H. / Gu, Y. / Chen, H. / Sickmier, E.A. / Manzanillo, P. / Huang, X.
External linksPLoS ONE / PubMed:30044821
MethodsX-ray diffraction
Resolution1.66 - 2.001 Å
Structure data

PDB-6czk:
Crystal structure of wild-type human pro-cathepsin H
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-6czs:
Crystal structure of human pro-cathepsin H C26S mutant
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / papain family cysteine peptidase / protein degradation in lysosome / inhibitory prodomain

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