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TitleCrystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217.
Journal, issue, pagesFebs Lett., Vol. 592, Page 2658-2667, Year 2018
Publish dateJul 9, 2018 (structure data deposition date)
AuthorsXu, M. / Chen, Y. / Xu, P. / Andreasen, P.A. / Jiang, L. / Li, J. / Huang, M.
External linksFebs Lett. / PubMed:30019481
MethodsX-ray diffraction
Resolution2.77 Å
Structure data

PDB-6a8o:
Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16
Method: X-RAY DIFFRACTION / Resolution: 2.77 Å

Chemicals

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-MRZ:
piperidine-1-carboximidamide

Source
  • mus musculus (house mouse)
  • synthemiopsis (insect)
KeywordsHYDROLASE / serine protease / murine plasma kallikrein

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