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TitleStructure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association.
Journal, issue, pagesStructure, Vol. 26, Page 1187-, Year 2018
Publish dateFeb 13, 2018 (structure data deposition date)
AuthorsDearborn, A.D. / Eren, E. / Watts, N.R. / Palmer, I.W. / Kaufman, J.D. / Steven, A.C. / Wingfield, P.T.
External linksStructure / PubMed:30017564
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-6cf2:
Crystal structure of HIV-1 Rev (residues 1-93)-RNA aptamer complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Source
  • oryctolagus cuniculus (rabbit)
  • human immunodeficiency virus 1
  • synthetic construct (others)
KeywordsRNA BINDING PROTEIN/RNA / HIV-1 / Rev / RNA aptamer / RNA BINDING PROTEIN-RNA complex

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