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TitleStructural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.
Journal, issue, pagesSci Rep, Vol. 8, Page 10317-10317, Year 2018
Publish dateFeb 10, 2018 (structure data deposition date)
AuthorsSalvador, G.H.M. / Dreyer, T.R. / Gomes, A.A.S. / Cavalcante, W.L.G. / Dos Santos, J.I. / Gandin, C.A. / de Oliveira Neto, M. / Gallacci, M. / Fontes, M.R.M.
External linksSci Rep / PubMed:29985425
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-6ce2:
Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-PE4:
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL / precipitant*YM

ChemComp-SVR:
8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON / medication*YM

ChemComp-HOH:
WATER

Source
  • bothrops moojeni (Brazilian lancehead)
KeywordsTOXIN / Myotoxin I / MjTX-I / PLA2-like / Suramin

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