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Structure paper

TitleTernary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.
Journal, issue, pagesNat Commun, Vol. 9, Page 2628-2628, Year 2018
Publish dateOct 19, 2017 (structure data deposition date)
AuthorsTrofimova, D. / Paydar, M. / Zara, A. / Talje, L. / Kwok, B.H. / Allingham, J.S.
External linksNat Commun / PubMed:29980677
MethodsX-ray diffraction
Resolution3.514 Å
Structure data

PDB-6bbn:
Crystal structure of a curved tubulin complex induced by the kinesin-13 Kif2A
Method: X-RAY DIFFRACTION / Resolution: 3.514 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • escherichia coli (E. coli)
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsMOTOR PROTEIN / Kinesin / Kif2A / microtubules / tubulin / kinesin-13

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