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Structure paper

TitleCrystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 25, Page 570-576, Year 2018
Publish dateMay 2, 2017 (structure data deposition date)
AuthorsAsada, H. / Horita, S. / Hirata, K. / Shiroishi, M. / Shiimura, Y. / Iwanari, H. / Hamakubo, T. / Shimamura, T. / Nomura, N. / Kusano-Arai, O. ...Asada, H. / Horita, S. / Hirata, K. / Shiroishi, M. / Shiimura, Y. / Iwanari, H. / Hamakubo, T. / Shimamura, T. / Nomura, N. / Kusano-Arai, O. / Uemura, T. / Suno, C. / Kobayashi, T. / Iwata, S.
External linksNat. Struct. Mol. Biol. / PubMed:29967536
MethodsX-ray diffraction
Resolution1.696 - 3.2 Å
Structure data

PDB-5xjm:
Complex structure of angiotensin II type 2 receptor with Fab
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-5xli:
Structure of anti-Angiotensin II type2 receptor antibody (D5711-4A03)
Method: X-RAY DIFFRACTION / Resolution: 1.696 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / class A GPCR / regulate human blood pressure / Angiotensin receptors / IMMUNE SYSTEM / antigbody / IgG / Fab

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