Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
Journal, issue, pages	J. Am. Chem. Soc., Vol. 140, Page 9299-9313, Year 2018
Publish date	May 2, 2018 (structure data deposition date)
Authors	Testa, A. / Lucas, X. / Castro, G.V. / Chan, K.H. / Wright, J.E. / Runcie, A.C. / Gadd, M.S. / Harrison, W.T.A. / Ko, E.J. / Fletcher, D. / Ciulli, A.
External links	J. Am. Chem. Soc. / PubMed:29949369
Methods	X-ray diffraction
Resolution	1.83 - 2.7 Å
Structure data	PDB-6gfx: pVHL:EloB:EloC in complex with modified HIF-1a CODD peptide containing (3R,4S)-3-fluoro-4-hydroxyproline (ligand 13a) Method: X-RAY DIFFRACTION / Resolution: 1.83 Å PDB-6gfy: pVHL:EloB:EloC in complex with modified VH032 containing (3R,4S)-3-fluoro-4-hydroxyproline (ligand 14a) Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-6gfz: pVHL:EloB:EloC in complex with modified VH032 containing (3S,4S)-3-fluoro-4-hydroxyproline (ligand 14b) Method: X-RAY DIFFRACTION / Resolution: 2.3 Å
Chemicals	ChemComp-HOH: WATER ChemComp-EXH: (2~{R},3~{R},4~{S})-1-[(2~{S})-2-acetamido-3,3-dimethyl-butanoyl]-3-fluoranyl-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide ChemComp-EXE: (2~{R},3~{S},4~{S})-1-[(2~{S})-2-acetamido-3,3-dimethyl-butanoyl]-3-fluoranyl-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide
Source	homo sapiens (human)
Keywords	LIGASE / PROTEIN-PEPTIDE COMPLEX / UBIQUITIN LIGASE / HYPOXIA INDUCIBLE FACTOR / protein complex / fluorinated hydroxyproline