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TitleStructural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus.
Journal, issue, pagesJ. Virol., Vol. 92, Year 2018
Publish dateJun 6, 2018 (structure data deposition date)
AuthorsLin, Q. / Li, T. / Chen, Y. / Lau, S.Y. / Wei, M. / Zhang, Y. / Zhang, Z. / Yao, Q. / Li, J. / Li, Z. ...Lin, Q. / Li, T. / Chen, Y. / Lau, S.Y. / Wei, M. / Zhang, Y. / Zhang, Z. / Yao, Q. / Li, J. / Li, Z. / Wang, D. / Zheng, Q. / Yu, H. / Gu, Y. / Zhang, J. / Chen, H. / Li, S. / Xia, N.
External linksJ. Virol. / PubMed:29925655
MethodsX-ray diffraction
Resolution2.3 - 2.329 Å
Structure data

PDB-6a0x:
Crystal structure of broadly neutralizing antibody 13D4
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6a0z:
Crystal structure of broadly neutralizing antibody 13D4 bound to H5N1 influenza hemagglutinin, HA head region
Method: X-RAY DIFFRACTION / Resolution: 2.329 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • mus musculus (house mouse)
  • influenza a virus
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / Antibody / VIRAL PROTEIN/IMMUNE SYSTEM / Immune complex / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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