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Structure paper

TitleCrystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
Journal, issue, pagesIUCrJ, Vol. 5, Page 223-235, Year 2018
Publish dateSep 6, 2016 (structure data deposition date)
AuthorsSaez-Ayala, M. / Yekwa, E.L. / Carcelli, M. / Canard, B. / Alvarez, K. / Ferron, F.
External linksIUCrJ / PubMed:29765612
MethodsX-ray diffraction
Resolution1.88 - 2.51 Å
Structure data

PDB-5ltf:
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease complexed with catalytic ions
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

PDB-5ltn:
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease complexed with DPBA
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-5lts:
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease Mutant D118A
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-5t2t:
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease bound to compound L742001
Method: X-RAY DIFFRACTION / Resolution: 1.967 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-XI7:
2-4-DIOXO-4-PHENYLBUTANOIC ACID

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NA:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-0N8:
(2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid

Source
  • lymphocytic choriomeningitis mammarenavirus
KeywordsTRANSFERASE / Endonuclease / LCMV Arenavirus / LCMV Arenavirus DPBA / mammarenavirus / LCMV / inhibitor

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