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-Structure paper
Title | Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 28, Page 2195-2200, Year 2018 |
Publish date | Jan 11, 2018 (structure data deposition date) |
![]() | Veenstra, S.J. / Rueeger, H. / Voegtle, M. / Lueoend, R. / Holzer, P. / Hurth, K. / Tintelnot-Blomley, M. / Frederiksen, M. / Rondeau, J.M. / Jacobson, L. ...Veenstra, S.J. / Rueeger, H. / Voegtle, M. / Lueoend, R. / Holzer, P. / Hurth, K. / Tintelnot-Blomley, M. / Frederiksen, M. / Rondeau, J.M. / Jacobson, L. / Staufenbiel, M. / Neumann, U. / Machauer, R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.54 Å |
Structure data | ![]() PDB-6fgy: |
Chemicals | ![]() ChemComp-D9W: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / OXAZINE |