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-Structure paper
Title | Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis. |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 4203-4212, Year 2018 |
Publish date | Mar 5, 2018 (structure data deposition date) |
Authors | Reis, J. / Manzella, N. / Cagide, F. / Mialet-Perez, J. / Uriarte, E. / Parini, A. / Borges, F. / Binda, C. |
External links | J. Med. Chem. / PubMed:29648817 |
Methods | X-ray diffraction |
Resolution | 1.6 - 1.8 Å |
Structure data | PDB-6fvz: PDB-6fw0: PDB-6fwc: |
Chemicals | ChemComp-FAD: ChemComp-E8Z: ChemComp-C15: ChemComp-GOL: ChemComp-HOH: ChemComp-E92: ChemComp-E98: |
Source |
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Keywords | FLAVOPROTEIN / Parkinson's disease / drug design / chromone / inhibitor |