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Structure paper

TitleCrystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
Journal, issue, pagesBiochemistry, Vol. 57, Page 3134-3145, Year 2018
Publish dateJan 8, 2018 (structure data deposition date)
AuthorsTu, Y. / Kreinbring, C.A. / Hill, M. / Liu, C. / Petsko, G.A. / McCune, C.D. / Berkowitz, D.B. / Liu, D. / Ringe, D.
External linksBiochemistry / PubMed:29630349
MethodsX-ray diffraction
Resolution1.37 - 2.3 Å
Structure data

PDB-6c2h:
Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the Catalytic Core
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

PDB-6c2q:
Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PLP-L-Serine Intermediate
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

PDB-6c2z:
Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PLP-Aminoacrylate Intermediate
Method: X-RAY DIFFRACTION / Resolution: 1.37 Å

PDB-6c4p:
Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PMP Complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-ACT:
ACETATE ION

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-EVM:
L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene]

ChemComp-P1T:
2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsLYASE / CBS / synthase / PLP

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