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TitleBAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Journal, issue, pagesNat Commun, Vol. 9, Page 1200-1200, Year 2018
Publish dateAug 25, 2017 (structure data deposition date)
AuthorsShin, W. / Lee, H.T. / Lim, H. / Lee, S.H. / Son, J.Y. / Lee, J.U. / Yoo, K.Y. / Ryu, S.E. / Rhie, J. / Lee, J.Y. / Heo, Y.S.
External linksNat Commun / PubMed:29572471
MethodsX-ray diffraction
Resolution1.9 - 2.05 Å
Structure data

PDB-5y9j:
BAFF in complex with belimumab
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-5y9k:
Structure of the belimumab Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / BAFF / belimumab / antibody / lupus

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