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Structure paper

TitleStructural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
Journal, issue, pagesFEBS J., Vol. 285, Page 1701-1714, Year 2018
Publish dateAug 18, 2017 (structure data deposition date)
AuthorsBaral, P.K. / Swayampakula, M. / Aguzzi, A. / James, M.N.G.
External linksFEBS J. / PubMed:29569342
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-6aq7:
Structure of POM6 FAB fragment complexed with mouse PrPc
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-TCE:
3,3',3''-phosphanetriyltripropanoic acid

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Prion / antibody / chaperone / antigen-antibody

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