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TitleAnticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
Journal, issue, pagesStructure, Vol. 26, Page 649-656.e3, Year 2018
Publish dateFeb 10, 2017 (structure data deposition date)
AuthorsSchiefner, A. / Gebauer, M. / Richter, A. / Skerra, A.
External linksStructure / PubMed:29526433
MethodsX-ray diffraction
Resolution1.6 - 3 Å
Structure data

PDB-5n47:
Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5n48:
Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / LIPOCALIN / ANTICALIN / LIPOCALIN-BASED BINDING PROTEIN / HUMAN FIBRONECTIN / ONCOFETAL SPLICE VARIANT / FN TYPE III DOMAIN / EXTRA-DOMAIN B / EIIIB / ED-B / EXTRACELLULAR MATRIX / STRUCTURAL PROTEIN

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