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Structure paper

TitleCharacterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling.
Journal, issue, pagesAngiogenesis, Vol. 21, Page 533-543, Year 2018
Publish dateSep 10, 2017 (structure data deposition date)
AuthorsThieltges, K.M. / Avramovic, D. / Piscitelli, C.L. / Markovic-Mueller, S. / Binz, H.K. / Ballmer-Hofer, K.
External linksAngiogenesis / PubMed:29502220
MethodsX-ray diffraction
Resolution2.38 Å
Structure data

PDB-5oyj:
Crystal structure of VEGFR-2 domains 4-5 in complex with DARPin D4b
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-CAC:
CACODYLATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / glycoprotein receptor kinase designed ankyrin repeat protein angiogenesis

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