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Structure paper

TitleA Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Journal, issue, pagesFront Immunol, Vol. 9, Page 99-99, Year 2018
Publish dateNov 17, 2016 (structure data deposition date)
AuthorsToor, J.S. / Rao, A.A. / McShan, A.C. / Yarmarkovich, M. / Nerli, S. / Yamaguchi, K. / Madejska, A.A. / Nguyen, S. / Tripathi, S. / Maris, J.M. ...Toor, J.S. / Rao, A.A. / McShan, A.C. / Yarmarkovich, M. / Nerli, S. / Yamaguchi, K. / Madejska, A.A. / Nguyen, S. / Tripathi, S. / Maris, J.M. / Salama, S.R. / Haussler, D. / Sgourakis, N.G.
External linksFront Immunol / PubMed:29441070
MethodsX-ray diffraction
Resolution1.697 - 2.9503 Å
Structure data

PDB-5txs:
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Method: X-RAY DIFFRACTION / Resolution: 1.697 Å

PDB-5vz5:
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Method: X-RAY DIFFRACTION / Resolution: 2.5901 Å

PDB-6at9:
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101
Method: X-RAY DIFFRACTION / Resolution: 2.9503 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / lymphoma kinase-derived neuroblastoma tumor antigen / Human Major Histocompatibility Complex Class I / MHC-I / Complex

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