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Structure paper

TitleCrystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway.
Journal, issue, pagesJ. Struct. Biol., Vol. 202, Page 229-235, Year 2018
Publish dateJun 10, 2017 (structure data deposition date)
AuthorsKluza, A. / Niedzialkowska, E. / Kurpiewska, K. / Wojdyla, Z. / Quesne, M. / Kot, E. / Porebski, P.J. / Borowski, T.
External linksJ. Struct. Biol. / PubMed:29408320
MethodsX-ray diffraction
Resolution1.85 - 1.97 Å
Structure data

PDB-5o7y:
Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum in complex with succinate
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-5o9w:
Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum in complex with 2-oxoglutarate
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-SIN:
SUCCINIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-UNX:
Unknown entry

ChemComp-NA:
Unknown entry

Source
  • papaver somniferum (opium poppy)
KeywordsOXIDOREDUCTASE / 2-oxoglutarate dependent dioxygenase / morphine biosynthesis / oripavine / thebaine

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