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| Title | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 9, Page 476-476, Year 2018 |
| Publish date | Dec 5, 2016 (structure data deposition date) |
Authors | Zheng, Y. / Sethi, R. / Mangala, L.S. / Taylor, C. / Goldsmith, J. / Wang, M. / Masuda, K. / Karaminejadranjbar, M. / Mannion, D. / Miranda, F. ...Zheng, Y. / Sethi, R. / Mangala, L.S. / Taylor, C. / Goldsmith, J. / Wang, M. / Masuda, K. / Karaminejadranjbar, M. / Mannion, D. / Miranda, F. / Herrero-Gonzalez, S. / Hellner, K. / Chen, F. / Alsaadi, A. / Albukhari, A. / Fotso, D.C. / Yau, C. / Jiang, D. / Pradeep, S. / Rodriguez-Aguayo, C. / Lopez-Berestein, G. / Knapp, S. / Gray, N.S. / Campo, L. / Myers, K.A. / Dhar, S. / Ferguson, D. / Bast, R.C. / Sood, A.K. / von Delft, F. / Ahmed, A.A. |
External links | Nat Commun / PubMed:29396402 |
| Methods | X-ray diffraction |
| Resolution | 1.8 - 2.48 Å |
| Structure data | ![]() PDB-5mkv: ![]() PDB-5mle: |
| Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-PEG: ![]() ChemComp-NI: |
| Source |
|
Keywords | HYDROLASE / CRMP2 / Ovarian cancer / Microtubule associated protein / phospho-mutant |
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homo sapiens (human)
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