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Structure paper

TitleAtomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.
Journal, issue, pagesNature, Vol. 553, Page 526-529, Year 2018
Publish dateMar 20, 2017 (structure data deposition date)
AuthorsDiver, M.M. / Pedi, L. / Koide, A. / Koide, S. / Long, S.B.
External linksNature / PubMed:29342140
MethodsX-ray diffraction
Resolution2.3 - 4 Å
Structure data

PDB-5v7p:
Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5vg9:
Structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase) without a monobody
Method: X-RAY DIFFRACTION / Resolution: 4 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-UND:
UNDECANE

ChemComp-D10:
DECANE

ChemComp-MPG:
[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate

ChemComp-HOH:
WATER

Source
  • tribolium castaneum (red flour beetle)
  • synthetic construct (others)
KeywordsTRANSFERASE / membrane protein / membrane enzyme / methyltransferase / LCP

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