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TitleStructural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
Journal, issue, pagesBiochemistry, Vol. 57, Page 574-584, Year 2018
Publish dateMay 1, 2017 (structure data deposition date)
AuthorsNocek, B. / Reidl, C. / Starus, A. / Heath, T. / Bienvenue, D. / Osipiuk, J. / Jedrzejczak, R. / Joachimiak, A. / Becker, D.P. / Holz, R.C.
External linksBiochemistry / PubMed:29272107
MethodsX-ray diffraction
Resolution1.954 Å
Structure data

PDB-5vo3:
Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)
Method: X-RAY DIFFRACTION / Resolution: 1.954 Å

Chemicals

ChemComp-SIN:
SUCCINIC ACID

ChemComp-API:
2,6-DIAMINOPIMELIC ACID

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae (bacteria)
KeywordsHYDROLASE / DapE / hydrolaze / Succinic acid / diaminopimelic acid / M28 / Structural Genomics / PSI-Biology

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