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Structure paper

TitleCrystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 1317-1329, Year 2018
Publish dateJul 18, 2017 (structure data deposition date)
AuthorsBitra, A. / Doukov, T. / Wang, J. / Picarda, G. / Benedict, C.A. / Croft, M. / Zajonc, D.M.
External linksJ. Biol. Chem. / PubMed:29242193
MethodsX-ray diffraction
Resolution2.3 - 2.95 Å
Structure data

PDB-5wi8:
Crystal structure of murine 4-1BB from HEK293T cells in P21 space group
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-5wiw:
Crystal structure of murine 4-1BB N128A mutant from HEK293T cells in P43 space group
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5wjf:
Crystal structure of murine 4-1BB from HEK293T cells in P21212 space group
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Tumor necrosis factor / apoptosis

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