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TitleRedox Regulation of a Gain-of-Function Mutation (N308D) in SHP2 Noonan Syndrome.
Journal, issue, pagesACS Omega, Vol. 2, Page 8313-8318, Year 2017
Publish dateAug 28, 2017 (structure data deposition date)
AuthorsMachado, L.E.S.F. / Critton, D.A. / Page, R. / Peti, W.
External linksACS Omega / PubMed:29214238
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6atd:
Oxidized SHP2 forms a disulfide bond between Cys367 and Cys459
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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