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TitleThe Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria.
Journal, issue, pagesACS Chem. Biol., Vol. 13, Page 131-140, Year 2018
Publish dateJun 30, 2017 (structure data deposition date)
AuthorsTersa, M. / Raich, L. / Albesa-Jove, D. / Trastoy, B. / Prandi, J. / Gilleron, M. / Rovira, C. / Guerin, M.E.
External linksACS Chem. Biol. / PubMed:29185694
MethodsX-ray diffraction
Resolution2.41 Å
Structure data

PDB-5oce:
THE MOLECULAR MECHANISM OF SUBSTRATE RECOGNITION AND CATALYSIS OF THE MEMBRANE ACYLTRANSFERASE PatA -- Complex of PatA with palmitate, mannose, and palmitoyl-6-mannose
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-PLM:
PALMITIC ACID

ChemComp-BMA:
beta-D-mannopyranose

ChemComp-9R2:
[(2~{R},3~{S},4~{S},5~{S},6~{S})-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl hexadecanoate

ChemComp-HOH:
WATER

Source
  • mycobacterium smegmatis (strain atcc 700084 / mc(2)155) (bacteria)
KeywordsTRANSFERASE / acyltransferase / glycolipid biosynthesis

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