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Structure paper

TitleDNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Journal, issue, pagesBiochimie, Vol. 146, Page 87-96, Year 2018
Publish dateDec 7, 2016 (structure data deposition date)
Authorsde Barros, A.C. / Takeda, A.A.S. / Dreyer, T.R. / Velazquez-Campoy, A. / Kobe, B. / Fontes, M.R.M.
External linksBiochimie / PubMed:29175432
MethodsX-ray diffraction
Resolution2.1 - 2.171 Å
Structure data

PDB-5u5p:
Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide
Method: X-RAY DIFFRACTION / Resolution: 2.171 Å

PDB-5u5r:
Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a PMS2 NLS Peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-DTT:
2,3-DIHYDROXY-1,4-DITHIOBUTANE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Nuclear transport / Importin-alpha / MLH1 / NLS / PMS2

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