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-Structure paper
Title | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E10578-E10585, Year 2017 |
Publish date | Nov 3, 2017 (structure data deposition date) |
Authors | Ring, N.G. / Herndler-Brandstetter, D. / Weiskopf, K. / Shan, L. / Volkmer, J.P. / George, B.M. / Lietzenmayer, M. / McKenna, K.M. / Naik, T.J. / McCarty, A. ...Ring, N.G. / Herndler-Brandstetter, D. / Weiskopf, K. / Shan, L. / Volkmer, J.P. / George, B.M. / Lietzenmayer, M. / McKenna, K.M. / Naik, T.J. / McCarty, A. / Zheng, Y. / Ring, A.M. / Flavell, R.A. / Weissman, I.L. |
External links | Proc. Natl. Acad. Sci. U.S.A. / PubMed:29158380 |
Methods | X-ray diffraction |
Resolution | 2.191 Å |
Structure data | PDB-6bit: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / Macrophage / Neutrophil / Phagocytosis / Myeloid / Immune checkpoint / CD47 / SIRP / Cancer immunotherapy |