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TitleMutation of Asn-475 in the Venezuelan Equine Encephalitis Virus nsP2 Cysteine Protease Leads to a Self-Inhibited State.
Journal, issue, pagesBiochemistry, Vol. 56, Page 6221-6230, Year 2017
Publish dateOct 20, 2017 (structure data deposition date)
AuthorsCompton, J.R. / Mickey, M.J. / Hu, X. / Marugan, J.J. / Legler, P.M.
External linksBiochemistry / PubMed:29064679
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6bcm:
Structure of a Self-inhibited N475A variant of the Venezuelan Equine Encephalitis Virus (VEEV) nsP2 cysteine protease
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • venezuelan equine encephalitis virus
KeywordsVIRAL PROTEIN / alphavirus / nsP2 / nonstructural protein / cysteine protease / self-inhibited / N475A / S-adenosyl-L-methionine methyltransferase

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