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TitleThree-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Journal, issue, pagesNat Commun, Vol. 8, Page 979-979, Year 2017
Publish dateSep 9, 2016 (structure data deposition date)
AuthorsSankhala, R.S. / Lokareddy, R.K. / Begum, S. / Pumroy, R.A. / Gillilan, R.E. / Cingolani, G.
External linksNat Commun / PubMed:29042532
MethodsX-ray diffraction
Resolution2.631 - 3.45 Å
Structure data

PDB-5t94:
Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
Method: X-RAY DIFFRACTION / Resolution: 2.631 Å

PDB-5tbk:
Crystal structure of human importin a3 bound to RCC1
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / NUCLEAR PROTEIN / Nuclear Import / Importin alpha / RCC1 like Domain / RLD / NLS / PROTEIN TRANSPORT - NUCLEAR PROTEIN complex / RCC1 like Domain (RLD)

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