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Structure paper

TitleA structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.
Journal, issue, pagesNucleic Acids Res., Vol. 45, Page 12529-12535, Year 2017
Publish dateFeb 27, 2018 (structure data deposition date)
AuthorsKanazawa, H. / Baba, F. / Koganei, M. / Kondo, J.
External linksNucleic Acids Res. / PubMed:29036479
MethodsX-ray diffraction
Resolution2.1 - 3.5 Å
Structure data

PDB-5zeg:
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5zei:
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with geneticin
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5zej:
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-5zem:
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in the presence of gentamicin
Method: X-RAY DIFFRACTION / Resolution: 3.103 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GET:
GENETICIN / antibiotic*YM

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

Source
  • synthetic construct (others)
KeywordsRNA / ribosome / aminoglycoside / antibiotic-resistance

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