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TitleThe effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of alpha-dystroglycan.
Journal, issue, pagesPLoS ONE, Vol. 12, Page e0186110-e0186110, Year 2017
Publish dateFeb 8, 2017 (structure data deposition date)
AuthorsCovaceuszach, S. / Bozzi, M. / Bigotti, M.G. / Sciandra, F. / Konarev, P.V. / Brancaccio, A. / Cassetta, A.
External linksPLoS ONE / PubMed:29036200
MethodsX-ray diffraction
Resolution1.701 - 1.8 Å
Structure data

PDB-5n30:
Crystal structure of the V72I mutant of the mouse alpha-Dystroglycan N-terminal region
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5n4h:
Crystal structure of the D109N mutant of the mouse alpha-Dystroglycan N-terminal region
Method: X-RAY DIFFRACTION / Resolution: 1.701 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsCELL ADHESION / Dystroglycan Cell Adhesion Laminin Binding / Dystroglycan / Laminin Binding

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