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Structure paper

TitleIntramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 19024-19033, Year 2017
Publish dateJul 18, 2017 (structure data deposition date)
AuthorsEmptage, R.P. / Schoenberger, M.J. / Ferguson, K.M. / Marmorstein, R.
External linksJ. Biol. Chem. / PubMed:28972186
MethodsX-ray diffraction
Resolution2.495 Å
Structure data

PDB-5wi2:
Crystal structure of the KA1 domain from human Chk1
Method: X-RAY DIFFRACTION / Resolution: 2.495 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase / Checkpoint / Autoinhibition

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