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TitleUbiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Journal, issue, pagesMol. Cell, Vol. 68, Page 233-246.e5, Year 2017
Publish dateJul 17, 2017 (structure data deposition date)
AuthorsMichel, M.A. / Swatek, K.N. / Hospenthal, M.K. / Komander, D.
External linksMol. Cell / PubMed:28943312
MethodsX-ray diffraction
Resolution2.5 - 3.8 Å
Structure data

PDB-5ohl:
K6-specific affimer bound to K6 diUb
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5ohm:
K33-specific affimer bound to K33 diUb
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

PDB-5ohv:
K33-specific affimer bound to K33 diUb
Method: X-RAY DIFFRACTION / Resolution: 2.801 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / ubiquitin / cystatin / affimer

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